They are used with uncountable nouns.

A large amount of – A small amount of

A large quantity of – A small quantity of

A good deal of – A great deal of

• They are trying to bring in a large amount of cocaine.

• I try to save a small amount of money every month.

• Sally spends a good deal of her time at home.

• He made a great deal of effort to help us.

• Police found a large quantity of heroin in the car.

• We bought a small quantity of vinegar.